Below-normal amounts of the protein TGFBR2 may be predictive of breast cancer resistance to the anti-estrogen drug tamoxifen, according to study results.Estrogen is a hormone that forces cells to grow and divide while the transforming growth factor (TGF)-beta cell signaling pathway exerts effects of growth-inhibition, according to study background. Both estrogen and TGF-beta signaling pathways interact — directly and indirectly — and if there is an abnormality with one pathway, it can possibly interfere with the activation of the other.
No comments:
Post a Comment