Study: Poly-L-lactic acid improved hill and valley acne scarring

Injectable poly-L-lactic acid treatment improved hill and valley acne scarring and was well-tolerated by patients, according to study results.In a single-arm, unblinded open-label phase 2 study conducted between October 2008 and September 2009, researchers in Canada injected poly-L-lactic acid over three to four serial treatments in 4-week intervals to 22 patients (mean age, 37.6 years). Likert scales, based on comparisons of photos taken at baseline to photos taken at treatment visits 2 to 4 and follow up, were used to determine the primary efficacy endpoint, the degree of change in hill and valley scarring by the physician, a blinded evaluator and the patient. There also was a secondary endpoint of patient satisfaction, also assessed by Likert scale.